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Literature summary extracted from

  • Varadi, A.; Tsuboi, T.; Johnson-Cadwell, L.I.; Allan, V.J.; Rutter, G.A.
    Kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells (2003), Biochem. Biophys. Res. Commun., 311, 272-282.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.6.1.2 cytoplasm
-
 Mus musculus 5737
-
5.6.1.3 cytosol the majority of large dense-core vesicle transport to the plasma membrane in beta-cells is mediated by kinesin I Mus musculus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n Mus musculus kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dyneien probably contrtibutes to the recovery of vesicles after rapid kiss-and-run exocytosis ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Mus musculus
-
 ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n Mus musculus kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dynein probably contributes to the recovery of vesicles after rapid kiss-and-run exocytosis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.2 Mus musculus
-
-
-
5.6.1.3 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.2 MIN-6 cell
-
 Mus musculus
-
5.6.1.3 MIN-6 cell
-
 Mus musculus
-
5.6.1.3 MIN-6 cell pancreatic beta-cell Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n
-
 Mus musculus ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.2 ATP + H2O + a dynein associated with a microtubule at position n kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dyneien probably contrtibutes to the recovery of vesicles after rapid kiss-and-run exocytosis Mus musculus ADP + phosphate + a dynein associated with a microtubule at position n-1 (toward the minus end)
-
 ?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n
-
 Mus musculus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?
5.6.1.3 ATP + H2O + a kinesin associated with a microtubule at position n kinesin I and cytoplasmic dynein orchestrate glucose-stimulated insulin-containing vesicle movements in clonal MIN6 beta-cells. The majority of transport of large dense-core vesicles in beta-cells is mediated by kinesin I, whilst dynein probably contributes to the recovery of vesicles after rapid kiss-and-run exocytosis Mus musculus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.3 kinesin I
-
 Mus musculus