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Literature summary extracted from

  • Turner, W.; Botha, F.C.
    Purification and kinetic properties of UDP-glucose dehydrogenase from sugarcane (2002), Arch. Biochem. Biophys., 407, 209-216.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.22 UDP-glucuronate competitive Saccharum spp.
1.1.1.22 UDP-xylose competitive Saccharum spp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.22 0.0187
-
 UDP-glucose pH 8.4, 25°C Saccharum spp.
1.1.1.22 0.0722
-
 NAD+ pH 8.4, 25°C Saccharum spp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.22 52000
-
 x * 52000, SDS-PAGE Saccharum spp.

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.22 Saccharum spp.
-
 hybrid
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.22
-
 Saccharum spp.

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.1.22 UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+ bi-uni-uni-bi mechanism Saccharum spp.
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.22 stem
-
 Saccharum spp.
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.22 2.17
-
 pH 8.4, 25°C Saccharum spp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.22 CTP-glucose + NAD+ 8% of activity with UDP-glucose Saccharum spp. CTP-glucuronate + NADH
-
 ir
1.1.1.22 additional information no substrate: ADP-glucose Saccharum spp. ?
-
 ?
1.1.1.22 TDP-glucose + NAD+ 2% of activity with UDP-glucose Saccharum spp. TDP-glucuronate + NADH
-
 ir
1.1.1.22 UDP-glucose + 2 NAD+ + H2O
-
 Saccharum spp. UDP-glucuronate + 2 NADH + 2 H+
-
 ir

Subunits

EC Number Subunits Comment Organism
1.1.1.22 ? x * 52000, SDS-PAGE Saccharum spp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.22 8.4
-
-
 Saccharum spp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.22 NAD+
-
 Saccharum spp.

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.22 0.017
-
 UDP-xylose pH 8.4, 25°C Saccharum spp.
1.1.1.22 0.292
-
 UDP-glucuronate pH 8.4, 25°C Saccharum spp.