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Literature summary extracted from

  • Kluettermann, K.; Tauchert, H.; Kleber, H.P.
    Synthesis of poly-beta-hydroxybutyrate by Agrobacterium radiobacter after growth on D-carnitine (2002), Acta Biotechnol., 22, 261-269.
No PubMed abstract available

Application

EC Number Application Comment Organism
1.1.1.254 synthesis Agrobacterium radiobacter can be used for conversion of the waste product L(-)-carnitine to poly-beta-hydroxybutyrate valuable as a biodegradable and biocompatible plastic Agrobacterium tumefaciens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.254 (S)-carnitine + NAD+ Agrobacterium tumefaciens substrate is derived as a waste product from chemical production procedures of L(-)-carnitine 3-dehydrocarnitine + NADH + H+ formation of poly-beta-hydroxybutyrate as a storage product ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.254 Agrobacterium tumefaciens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.1.1.254 (S)-carnitine + NAD+ = 3-dehydrocarnitine + NADH + H+ specific for the (S)-enantiomer of carnitine Agrobacterium tumefaciens
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.254 additional information organism is able to grow on synthetic D(+)-carnitine, but not on physiological L(-)-carnitine, as sole carbon and nitrogen source Agrobacterium tumefaciens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.254 additional information
-
-
 Agrobacterium tumefaciens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.254 (S)-carnitine + NAD+
-
 Agrobacterium tumefaciens 3-dehydrocarnitine + NADH + H+
-
 ?
1.1.1.254 (S)-carnitine + NAD+ substrate is derived as a waste product from chemical production procedures of L(-)-carnitine Agrobacterium tumefaciens 3-dehydrocarnitine + NADH + H+ formation of poly-beta-hydroxybutyrate as a storage product ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.254 NAD+ specific for Agrobacterium tumefaciens