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Literature summary extracted from

  • Froehlich, R.F.G.; Zabelinskaja-Mackova, A.A.; Fechter, M.H.; Griengl, H.
    Novel access to chiral 1,1'-disubstituted ferrocene derivatives via double stereoselective cyanohydrin synthesis exploiting the hydroxynitrile lyase from Hevea brasiliensis (2003), Tetrahedron, 14, 355-362.
No PubMed abstract available

Application

EC Number Application Comment Organism
4.1.2.47 synthesis production of chiral ferrocene derivatives as ligands in asymmetric catalysis, to bioelectrochemistry and development of new pharmaceuticals against malaria Hevea brasiliensis

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.47 Hevea brasiliensis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.47 acetone cyanhydrin
-
Hevea brasiliensis HCN + acetone
-
?
4.1.2.47 HCN + 1,1'-diformylferrocene
-
Hevea brasiliensis (R,R)-1,1-bis(cyanohydroxymethyl)ferrocene
-
?
4.1.2.47 HCN + ferrocene aldehyde
-
Hevea brasiliensis ?
-
?
4.1.2.47 HCN + formylferrocene
-
Hevea brasiliensis (R)-(cyanohydroxymethyl)ferrocene
-
?
4.1.2.47 additional information acetylferrocene and 1,1'-diacetylferrocene are not transformed with this enzyme Hevea brasiliensis ?
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.47 (S)-HbHNL
-
Hevea brasiliensis
4.1.2.47 Hydroxynitrile lyase
-
Hevea brasiliensis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.2.47 4.8
-
conversion of formylferrocene Hevea brasiliensis

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
4.1.2.47 4.8
-
still stable at this value Hevea brasiliensis