Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Briknarova, K.; Grishaev, A.; Banyai, L.; Tordai, H.; Patthy, L.; Llinas, M.
    The second type II module from human matrix metalloproteinase 2: structure, function and dynamics (1999), Structure, 7, 1235-1245.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.24 membrane-type 1 matrix metalloproteinase activity in the extracellular environment is modulated by this activator Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.24 second fibronectin type II module, residues 278-336, produced in Escherichia coli Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.24 additional information Homo sapiens important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.24 Homo sapiens
-
 human
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.24 second fibronectin type II module, residues 278-336, produced in Escherichia coli Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.24 Collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.24 Elastin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.24 Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.24 Laminin + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.24 additional information important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.24 72 kDa type IV collagenase
-
 Homo sapiens
3.4.24.24 gelatinase A
-
 Homo sapiens
3.4.24.24 human matrix metalloproteinase 2
-
 Homo sapiens
3.4.24.24 MMP-2
-
 Homo sapiens