BRENDA - Enzyme Database

Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold

McCarthy, A.A.; Baker, H.M.; Shewry, S.C.; Patchett, M.L.; Baker, E.N.; Structure 9, 637-646 (2001)

Data extracted from this reference:

Crystallization (Commentary)
EC Number
Crystallization (Commentary)
Organism
5.1.99.1
crystallization of native, Co2+-substituted and SeMet-substituted enzyme by hanging-drop vapour-diffusion method
Propionibacterium freudenreichii subsp. shermanii
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
5.1.99.1
additional information
His12, Gln65, His91 and Glu141 provide a binding site for a divalent metal ion, as shown by binding of Co2+
Propionibacterium freudenreichii subsp. shermanii
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
5.1.99.1
additional information
Propionibacterium freudenreichii subsp. shermanii
essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine
?
-
Propionibacterium freudenreichii subsp. shermanii
?
Organism
EC Number
Organism
UniProt
Commentary
Textmining
5.1.99.1
Propionibacterium freudenreichii subsp. shermanii
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
5.1.99.1
(R)-methylmalonyl-CoA
-
653930
Propionibacterium freudenreichii subsp. shermanii
(S)-methylmalonyl-CoA
-
653930
Propionibacterium freudenreichii subsp. shermanii
?
5.1.99.1
additional information
essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine
653930
Propionibacterium freudenreichii subsp. shermanii
?
-
653930
Propionibacterium freudenreichii subsp. shermanii
?
Synonyms
EC Number
Synonyms
Commentary
Organism
5.1.99.1
MMCE
-
Propionibacterium freudenreichii subsp. shermanii
Crystallization (Commentary) (protein specific)
EC Number
Crystallization
Organism
5.1.99.1
crystallization of native, Co2+-substituted and SeMet-substituted enzyme by hanging-drop vapour-diffusion method
Propionibacterium freudenreichii subsp. shermanii
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
5.1.99.1
additional information
His12, Gln65, His91 and Glu141 provide a binding site for a divalent metal ion, as shown by binding of Co2+
Propionibacterium freudenreichii subsp. shermanii
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
5.1.99.1
additional information
Propionibacterium freudenreichii subsp. shermanii
essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine
?
-
Propionibacterium freudenreichii subsp. shermanii
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
5.1.99.1
(R)-methylmalonyl-CoA
-
653930
Propionibacterium freudenreichii subsp. shermanii
(S)-methylmalonyl-CoA
-
653930
Propionibacterium freudenreichii subsp. shermanii
?
5.1.99.1
additional information
essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine
653930
Propionibacterium freudenreichii subsp. shermanii
?
-
653930
Propionibacterium freudenreichii subsp. shermanii
?