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Literature summary extracted from

  • McCarthy, A.A.; Baker, H.M.; Shewry, S.C.; Patchett, M.L.; Baker, E.N.
    Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold (2001), Structure, 9, 637-646.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.1.99.1 crystallization of native, Co2+-substituted and SeMet-substituted enzyme by hanging-drop vapour-diffusion method Propionibacterium freudenreichii subsp. shermanii

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.1.99.1 additional information His12, Gln65, His91 and Glu141 provide a binding site for a divalent metal ion, as shown by binding of Co2+ Propionibacterium freudenreichii subsp. shermanii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.1.99.1 additional information Propionibacterium freudenreichii subsp. shermanii essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
5.1.99.1 Propionibacterium freudenreichii subsp. shermanii
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.1.99.1 (R)-methylmalonyl-CoA
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 Propionibacterium freudenreichii subsp. shermanii (S)-methylmalonyl-CoA
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 ?
5.1.99.1 additional information essential enzyme in the breakdown of odd-numbered fatty acids and of the amino acids valine, isoleucine, and methionine Propionibacterium freudenreichii subsp. shermanii ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.1.99.1 MMCE
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 Propionibacterium freudenreichii subsp. shermanii