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Literature summary extracted from

  • Chihade, J.W.; Brown, J.R.; Schimmel, P.R.; De Pouplana, L.R.
    Origin of mitochondria in relation to evolutionary history of eukaryotic alanyl-tRNA synthetase (2000), Proc. Natl. Acad. Sci. USA, 97, 12153-12157.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.1.1.7 gene alaS, DNA sequence determination and analysis, phylogenetic origin Giardia intestinalis
6.1.1.7 gene alaS, DNA sequence determination and analysis, phylogenetic origin Dictyostelium discoideum
6.1.1.7 gene alaS, DNA sequence determination and analysis, phylogenetic origin Drosophila melanogaster

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.1.1.7 mitochondrion
-
 Drosophila melanogaster 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.7 ATP + L-alanine + tRNAAla Giardia intestinalis
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
6.1.1.7 ATP + L-alanine + tRNAAla Dictyostelium discoideum
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
6.1.1.7 ATP + L-alanine + tRNAAla Drosophila melanogaster
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.7 Dictyostelium discoideum Q54Y20 gene alaS
-
6.1.1.7 Drosophila melanogaster Q9VRJ1 gene alaS is nuclear-encoded, mitochondrial isozyme
-
6.1.1.7 Giardia intestinalis Q9U022
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.7 ATP + L-alanine + tRNAAla
-
 Giardia intestinalis AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
6.1.1.7 ATP + L-alanine + tRNAAla
-
 Dictyostelium discoideum AMP + diphosphate + L-alanyl-tRNAAla
-
 ?
6.1.1.7 ATP + L-alanine + tRNAAla
-
 Drosophila melanogaster AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.7 Ala-tRNA synthetase
-
 Giardia intestinalis
6.1.1.7 Ala-tRNA synthetase
-
 Dictyostelium discoideum
6.1.1.7 Ala-tRNA synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanine transfer RNA synthetase
-
 Giardia intestinalis
6.1.1.7 Alanine transfer RNA synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanine transfer RNA synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanine translase
-
 Giardia intestinalis
6.1.1.7 Alanine translase
-
 Dictyostelium discoideum
6.1.1.7 Alanine translase
-
 Drosophila melanogaster
6.1.1.7 Alanine tRNA synthetase
-
 Giardia intestinalis
6.1.1.7 Alanine tRNA synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanine tRNA synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanine-transfer RNA ligase
-
 Giardia intestinalis
6.1.1.7 Alanine-transfer RNA ligase
-
 Dictyostelium discoideum
6.1.1.7 Alanine-transfer RNA ligase
-
 Drosophila melanogaster
6.1.1.7 alanine-tRNA ligase
-
 Giardia intestinalis
6.1.1.7 alanine-tRNA ligase
-
 Dictyostelium discoideum
6.1.1.7 alanine-tRNA ligase
-
 Drosophila melanogaster
6.1.1.7 Alanyl-transfer ribonucleate synthetase
-
 Giardia intestinalis
6.1.1.7 Alanyl-transfer ribonucleate synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanyl-transfer ribonucleate synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanyl-transfer ribonucleic acid synthetase
-
 Giardia intestinalis
6.1.1.7 Alanyl-transfer ribonucleic acid synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanyl-transfer ribonucleic acid synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanyl-transfer RNA synthetase
-
 Giardia intestinalis
6.1.1.7 Alanyl-transfer RNA synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanyl-transfer RNA synthetase
-
 Drosophila melanogaster
6.1.1.7 Alanyl-tRNA synthetase
-
 Giardia intestinalis
6.1.1.7 Alanyl-tRNA synthetase
-
 Dictyostelium discoideum
6.1.1.7 Alanyl-tRNA synthetase
-
 Drosophila melanogaster
6.1.1.7 AlaRS
-
 Giardia intestinalis
6.1.1.7 AlaRS
-
 Dictyostelium discoideum
6.1.1.7 AlaRS
-
 Drosophila melanogaster
6.1.1.7 Synthase, alanyl-transfer ribonucleate
-
 Giardia intestinalis
6.1.1.7 Synthase, alanyl-transfer ribonucleate
-
 Dictyostelium discoideum
6.1.1.7 Synthase, alanyl-transfer ribonucleate
-
 Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.7 ATP
-
 Giardia intestinalis
6.1.1.7 ATP
-
 Dictyostelium discoideum
6.1.1.7 ATP
-
 Drosophila melanogaster