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Literature summary extracted from

  • El-Ahmady, S.H.; Nessler, C.L.
    Cellular localization of tyrosine decarboxylase expression in transgenic opium poppy and tobacco (2001), Plant Cell Rep., 20, 313-317.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.25 expression of TyDC5 fused to beta-glucuronidase in Papaver somniferum and in Nicotiana tabacum Papaver somniferum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.25 L-Tyrosine Papaver somniferum first enzyme in poppy alkaloid biosynthesis, first biosynthetic step in the tetrahydroisoquinoline pathway, TyDC serves as a channel between the aromatic amino acids L-thyrosine and L-dopa and the biosynthesis of all of the opium poppy alkaloids Tyramine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.25 Papaver somniferum
-
 opium poppy, TyDC gene family with about 15 members, TyDC5
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.25 additional information recombinant TyDC5 expression pattern, not in poppy laticifers, about 15 members of the TyDC gene family show differences in developmental, tissue-specific and inducible gene expression Papaver somniferum
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4.1.1.25 root recombinant TyDC5, vascular cylinder surrounding the xylem Papaver somniferum
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4.1.1.25 shoot recombinant TyDC5, xylem parenchyma Papaver somniferum
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.25 L-Dopa
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 Papaver somniferum dopamine + CO2
-
 ?
4.1.1.25 L-Tyrosine very substrate-specific Papaver somniferum Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine first enzyme in poppy alkaloid biosynthesis, first biosynthetic step in the tetrahydroisoquinoline pathway, TyDC serves as a channel between the aromatic amino acids L-thyrosine and L-dopa and the biosynthesis of all of the opium poppy alkaloids Papaver somniferum Tyramine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.25 TYDC
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 Papaver somniferum