Any feedback?
Literature summary extracted from
- Differential expression of membrane and soluble adenylyl cyclase isoforms in cytotrophoblast cells and syncytiotrophoblasts of human placenta (2003), Placenta, 24, 648-657.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | Calmodulin | - |
Homo sapiens |  |
| 4.6.1.1 | G-protein | activation by betagamma subunits | Homo sapiens | |
| 4.6.1.1 | G-protein | betagamma subunit | Homo sapiens | |
| 4.6.1.1 | G-protein | betagamma subunits | Homo sapiens | |
| 4.6.1.1 | additional information | insensitive to either Ca2+ or betagamma subunits of G-proteins | Homo sapiens | |
| 4.6.1.1 | Protein kinase C | phosphorylation | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | Ca2+ | at low concentrations; inhibition by low concentrations | Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 4.6.1.1 | cytosol | - |
Homo sapiens | 5829 | - |
| 4.6.1.1 | membrane | - |
Homo sapiens | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.1 | Ca2+ | stimulation | Homo sapiens | |
| 4.6.1.1 | Ca2+ | activation | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.1 | ATP | Homo sapiens | - |
3',5'-cyclic AMP + diphosphate | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.1 | Homo sapiens | - |
isoenzyme AC5 | - |
| 4.6.1.1 | Homo sapiens | - |
isoenzyme AC9 | - |
| 4.6.1.1 | Homo sapiens | O43306 | isoenzyme AC | - |
| 4.6.1.1 | Homo sapiens | O60266 | isoenzyme AC3 | - |
| 4.6.1.1 | Homo sapiens | O95622 | isoenzyme AC4 | - |
| 4.6.1.1 | Homo sapiens | P40145 | isoenzyme AC8 | - |
| 4.6.1.1 | Homo sapiens | P51828 | isoenzyme AC7 | - |
| 4.6.1.1 | Homo sapiens | Q08462 | isoenzyme AC2 | - |
| 4.6.1.1 | Homo sapiens | Q08828 | isoenzyme AC1 | - |
| 4.6.1.1 | Homo sapiens | Q96PN6 | isoenzyme AC | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 4.6.1.1 | phosphoprotein | activation by protein kinase C phosphorylation | Homo sapiens |
| 4.6.1.1 | phosphoprotein | activytion by protein kinase C phosphorylation | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.1 | ATP | - |
Homo sapiens | 3',5'-cyclic AMP + diphosphate | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.6.1.1 | AC1 | - |
Homo sapiens |
| 4.6.1.1 | AC2 | - |
Homo sapiens |
| 4.6.1.1 | AC3 | - |
Homo sapiens |
| 4.6.1.1 | AC4 | - |
Homo sapiens |
| 4.6.1.1 | AC5 | - |
Homo sapiens |
| 4.6.1.1 | AC6 | - |
Homo sapiens |
| 4.6.1.1 | AC7 | - |
Homo sapiens |
| 4.6.1.1 | AC8 | - |
Homo sapiens |
| 4.6.1.1 | AC9 | - |
Homo sapiens |
| 4.6.1.1 | adenylyl cyclase | - |
Homo sapiens |
| 4.6.1.1 | soluble AC | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
