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Literature summary extracted from

  • Facchini, P.J.; Huber-Allanach, K.L.; Tari, L.W.
    Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications (2000), Phytochemistry, 54, 121-138.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Hordeum vulgare
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Petroselinum crispum
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Syringa vulgaris
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Sanguinaria canadensis
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Thalictrum rugosum
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Eschscholzia californica
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Cytisus scoparius
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Chondrodendron tomentosum
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Petunia sp.
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Arabidopsis thaliana
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Papaver somniferum
4.1.1.25 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Colchicum autumnale
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Drosophila melanogaster
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Sus scrofa
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Solanum lycopersicum
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Cinchona calisaya
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Catharanthus roseus
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Cinchona officinalis
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Camptotheca acuminata
4.1.1.28 pharmacology biosynthesis of pharmaceutically important monoterpenoid indole alkaloids Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.25
-
 Hordeum vulgare
4.1.1.25
-
 Petroselinum crispum
4.1.1.25
-
 Syringa vulgaris
4.1.1.25
-
 Sanguinaria canadensis
4.1.1.25
-
 Thalictrum rugosum
4.1.1.25
-
 Eschscholzia californica
4.1.1.25
-
 Cytisus scoparius
4.1.1.25
-
 Chondrodendron tomentosum
4.1.1.25
-
 Petunia sp.
4.1.1.25
-
 Arabidopsis thaliana
4.1.1.25
-
 Papaver somniferum
4.1.1.25
-
 Colchicum autumnale
4.1.1.28
-
 Drosophila melanogaster
4.1.1.28
-
 Sus scrofa
4.1.1.28
-
 Solanum lycopersicum
4.1.1.28
-
 Cinchona calisaya
4.1.1.28
-
 Cinchona officinalis
4.1.1.28
-
 Homo sapiens
4.1.1.28 TDC encoded by a single-copy gene,TDC gene used to transform tobacco, Canola and potato plants and callus and root cultures from Peganum harmala Catharanthus roseus
4.1.1.28 two autonomously regulated genes, TDC1 and TDC2 Camptotheca acuminata

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.25 L-2-aminoxy-3-phenylpropionate
-
 Eschscholzia californica
4.1.1.25 L-2-aminoxy-3-phenylpropionate
-
 Hordeum vulgare
4.1.1.25 L-2-aminoxy-3-phenylpropionate
-
 Syringa vulgaris
4.1.1.28 D-tryptophan non-competitive inhibitor Catharanthus roseus
4.1.1.28 tryptamine competitive inhibitor Catharanthus roseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.25 0.25
-
 L-Dopa no details of experimental conditions given Thalictrum rugosum
4.1.1.25 0.27
-
 L-tyrosine no details of experimental conditions given Thalictrum rugosum
4.1.1.25 1
-
 L-tyrosine
-
 Eschscholzia californica
4.1.1.25 1
-
 L-tyrosine
-
 Papaver somniferum
4.1.1.25 1
-
 L-Dopa
-
 Papaver somniferum
4.1.1.25 1.1
-
 L-Dopa
-
 Eschscholzia californica

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.25 112000
-
-
 Thalictrum rugosum
4.1.1.25 112000
-
-
 Eschscholzia californica
4.1.1.28 54000
-
 2 * 54000 Catharanthus roseus
4.1.1.28 115000
-
-
 Catharanthus roseus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.25 L-Tyrosine Hordeum vulgare
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Petroselinum crispum
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Syringa vulgaris
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Sanguinaria canadensis
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Thalictrum rugosum
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Eschscholzia californica
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Chondrodendron tomentosum
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Petunia sp.
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Arabidopsis thaliana
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Papaver somniferum
-
 Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine Colchicum autumnale
-
 Tyramine + CO2
-
 ?
4.1.1.28 L-tryptophan Sus scrofa
-
 tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Homo sapiens
-
 tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Solanum lycopersicum implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Cinchona calisaya implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Catharanthus roseus implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Cinchona officinalis implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan Camptotheca acuminata implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines tryptamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.25 Arabidopsis thaliana Q8RY79
-
-
4.1.1.25 Chondrodendron tomentosum
-
-
-
4.1.1.25 Colchicum autumnale
-
-
-
4.1.1.25 Cytisus scoparius
-
-
-
4.1.1.25 Eschscholzia californica
-
 california poppy
-
4.1.1.25 Hordeum vulgare
-
-
-
4.1.1.25 Papaver somniferum P54768 opium poppy
-
4.1.1.25 Petroselinum crispum
-
 parsley
-
4.1.1.25 Petunia sp.
-
-
-
4.1.1.25 Sanguinaria canadensis
-
-
-
4.1.1.25 Syringa vulgaris
-
-
-
4.1.1.25 Thalictrum rugosum
-
 meadow rue
-
4.1.1.28 Camptotheca acuminata P93082
-
-
4.1.1.28 Catharanthus roseus P17770
-
-
4.1.1.28 Cinchona calisaya
-
-
-
4.1.1.28 Cinchona officinalis
-
-
-
4.1.1.28 Drosophila melanogaster
-
 fruit fly
-
4.1.1.28 Homo sapiens P20711 human
-
4.1.1.28 Solanum lycopersicum
-
-
-
4.1.1.28 Sus scrofa
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.25
-
 Thalictrum rugosum
4.1.1.28
-
 Catharanthus roseus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.25 2-fluoro-L-tyrosine
-
 Eschscholzia californica 2-fluorotyramine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Hordeum vulgare dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Petroselinum crispum dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Syringa vulgaris dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Sanguinaria canadensis dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Thalictrum rugosum dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Eschscholzia californica dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Cytisus scoparius dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Chondrodendron tomentosum dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Petunia sp. dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Arabidopsis thaliana dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Papaver somniferum dopamine + CO2
-
 ?
4.1.1.25 L-Dopa
-
 Colchicum autumnale dopamine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Hordeum vulgare Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Petroselinum crispum Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Syringa vulgaris Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Sanguinaria canadensis Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Thalictrum rugosum Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Eschscholzia californica Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Chondrodendron tomentosum Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Petunia sp. Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Arabidopsis thaliana Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Papaver somniferum Tyramine + CO2
-
 ?
4.1.1.25 L-Tyrosine
-
 Colchicum autumnale Tyramine + CO2
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Hordeum vulgare ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Petroselinum crispum ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Syringa vulgaris ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Sanguinaria canadensis ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Thalictrum rugosum ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Eschscholzia californica ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Cytisus scoparius ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Chondrodendron tomentosum ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Petunia sp. ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Arabidopsis thaliana ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Papaver somniferum ?
-
 ?
4.1.1.25 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, inactive toward L-phenylalanine and L-tryptophan Colchicum autumnale ?
-
 ?
4.1.1.28 4-fluoro-L-tryptophan
-
 Catharanthus roseus 4-fluorotryptamine + CO2
-
 ?
4.1.1.28 4-methyl-L-tryptophan
-
 Catharanthus roseus 4-methyltryptamine + CO2
-
 ?
4.1.1.28 5-fluoro-L-tryptophan
-
 Catharanthus roseus 5-fluorotryptamine + CO2
-
 ?
4.1.1.28 5-hydroxy-L-tryptophan
-
 Solanum lycopersicum 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 5-hydroxy-L-tryptophan
-
 Cinchona calisaya 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 5-hydroxy-L-tryptophan
-
 Catharanthus roseus 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 5-hydroxy-L-tryptophan
-
 Camptotheca acuminata 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 5-hydroxy-L-tryptophan
-
 Homo sapiens 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 5-hydroxytryptophan
-
 Cinchona officinalis 5-hydroxytryptamine + CO2
-
 ?
4.1.1.28 L-Dopa
-
 Drosophila melanogaster dopamine + CO2
-
 ?
4.1.1.28 L-Dopa
-
 Sus scrofa dopamine + CO2
-
 ?
4.1.1.28 L-Dopa
-
 Homo sapiens dopamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Sus scrofa tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Solanum lycopersicum tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Cinchona calisaya tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Catharanthus roseus tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Cinchona officinalis tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Camptotheca acuminata tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Homo sapiens tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines Solanum lycopersicum tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines Cinchona calisaya tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines Catharanthus roseus tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines Cinchona officinalis tryptamine + CO2
-
 ?
4.1.1.28 L-tryptophan implicated in the biosynthesis of the plant hormone indole-3-acetic acid, also involved in the formation of the monoamine serotonin, and of simple alkaloids such as the beta-carbolines Camptotheca acuminata tryptamine + CO2
-
 ?
4.1.1.28 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, L-tyrosine, L-phenylalanine and L-Dopa are not accepted as substrates Solanum lycopersicum ?
-
 ?
4.1.1.28 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, L-tyrosine, L-phenylalanine and L-Dopa are not accepted as substrates Cinchona calisaya ?
-
 ?
4.1.1.28 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, L-tyrosine, L-phenylalanine and L-Dopa are not accepted as substrates Catharanthus roseus ?
-
 ?
4.1.1.28 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, L-tyrosine, L-phenylalanine and L-Dopa are not accepted as substrates Cinchona officinalis ?
-
 ?
4.1.1.28 additional information exclusive substrate specificity for L-amino acids with either indole or phenol side chains, but not both, L-tyrosine, L-phenylalanine and L-Dopa are not accepted as substrates Camptotheca acuminata ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.25 homodimer
-
 Thalictrum rugosum
4.1.1.25 homodimer
-
 Eschscholzia californica
4.1.1.28 dimer 2 * 54000 Catharanthus roseus

Synonyms

EC Number Synonyms Comment Organism
4.1.1.25 AADC
-
 Hordeum vulgare
4.1.1.25 AADC
-
 Petroselinum crispum
4.1.1.25 AADC
-
 Syringa vulgaris
4.1.1.25 AADC
-
 Sanguinaria canadensis
4.1.1.25 AADC
-
 Thalictrum rugosum
4.1.1.25 AADC
-
 Eschscholzia californica
4.1.1.25 AADC
-
 Cytisus scoparius
4.1.1.25 AADC
-
 Chondrodendron tomentosum
4.1.1.25 AADC
-
 Petunia sp.
4.1.1.25 AADC
-
 Arabidopsis thaliana
4.1.1.25 AADC
-
 Papaver somniferum
4.1.1.25 AADC
-
 Colchicum autumnale
4.1.1.25 AtTYDC
-
 Arabidopsis thaliana
4.1.1.25 L-amino acid decarboxylase
-
 Hordeum vulgare
4.1.1.25 L-amino acid decarboxylase
-
 Petroselinum crispum
4.1.1.25 L-amino acid decarboxylase
-
 Syringa vulgaris
4.1.1.25 L-amino acid decarboxylase
-
 Sanguinaria canadensis
4.1.1.25 L-amino acid decarboxylase
-
 Thalictrum rugosum
4.1.1.25 L-amino acid decarboxylase
-
 Eschscholzia californica
4.1.1.25 L-amino acid decarboxylase
-
 Cytisus scoparius
4.1.1.25 L-amino acid decarboxylase
-
 Chondrodendron tomentosum
4.1.1.25 L-amino acid decarboxylase
-
 Petunia sp.
4.1.1.25 L-amino acid decarboxylase
-
 Arabidopsis thaliana
4.1.1.25 L-amino acid decarboxylase
-
 Papaver somniferum
4.1.1.25 L-amino acid decarboxylase
-
 Colchicum autumnale
4.1.1.25 PcTYDC2
-
 Petroselinum crispum
4.1.1.25 PsTYDC1
-
 Papaver somniferum
4.1.1.25 PsTYDC2
-
 Papaver somniferum
4.1.1.25 TYDC
-
 Hordeum vulgare
4.1.1.25 TYDC
-
 Petroselinum crispum
4.1.1.25 TYDC
-
 Syringa vulgaris
4.1.1.25 TYDC
-
 Sanguinaria canadensis
4.1.1.25 TYDC
-
 Thalictrum rugosum
4.1.1.25 TYDC
-
 Eschscholzia californica
4.1.1.25 TYDC
-
 Cytisus scoparius
4.1.1.25 TYDC
-
 Chondrodendron tomentosum
4.1.1.25 TYDC
-
 Petunia sp.
4.1.1.25 TYDC
-
 Arabidopsis thaliana
4.1.1.25 TYDC
-
 Papaver somniferum
4.1.1.25 TYDC
-
 Colchicum autumnale
4.1.1.25 tyrosine decarboxylase-2
-
 Petroselinum crispum
4.1.1.25 tyrosine/Dopa decarboxylase-1
-
 Papaver somniferum
4.1.1.25 tyrosine/Dopa decarboxylase-2
-
 Papaver somniferum
4.1.1.28 AADC
-
 Drosophila melanogaster
4.1.1.28 AADC
-
 Sus scrofa
4.1.1.28 AADC
-
 Solanum lycopersicum
4.1.1.28 AADC
-
 Cinchona calisaya
4.1.1.28 AADC
-
 Catharanthus roseus
4.1.1.28 AADC
-
 Cinchona officinalis
4.1.1.28 AADC
-
 Camptotheca acuminata
4.1.1.28 AADC
-
 Homo sapiens
4.1.1.28 CrTDC
-
 Catharanthus roseus
4.1.1.28 DDC
-
 Drosophila melanogaster
4.1.1.28 DDC
-
 Sus scrofa
4.1.1.28 DDC
-
 Homo sapiens
4.1.1.28 EC 4.1.1.27 formerly Solanum lycopersicum
4.1.1.28 EC 4.1.1.27 formerly Cinchona calisaya
4.1.1.28 EC 4.1.1.27 formerly Catharanthus roseus
4.1.1.28 EC 4.1.1.27 formerly Cinchona officinalis
4.1.1.28 EC 4.1.1.27 formerly Camptotheca acuminata
4.1.1.28 HsDDC
-
 Homo sapiens
4.1.1.28 L-amino acid decarboxylase
-
 Drosophila melanogaster
4.1.1.28 L-amino acid decarboxylase
-
 Sus scrofa
4.1.1.28 L-amino acid decarboxylase
-
 Solanum lycopersicum
4.1.1.28 L-amino acid decarboxylase
-
 Cinchona calisaya
4.1.1.28 L-amino acid decarboxylase
-
 Catharanthus roseus
4.1.1.28 L-amino acid decarboxylase
-
 Cinchona officinalis
4.1.1.28 L-amino acid decarboxylase
-
 Camptotheca acuminata
4.1.1.28 L-amino acid decarboxylase
-
 Homo sapiens
4.1.1.28 L-DOPA decarboxylase
-
 Drosophila melanogaster
4.1.1.28 L-DOPA decarboxylase
-
 Sus scrofa
4.1.1.28 L-DOPA decarboxylase
-
 Homo sapiens
4.1.1.28 L-Tryptophan decarboxylase
-
 Solanum lycopersicum
4.1.1.28 L-Tryptophan decarboxylase
-
 Cinchona calisaya
4.1.1.28 L-Tryptophan decarboxylase
-
 Catharanthus roseus
4.1.1.28 L-Tryptophan decarboxylase
-
 Cinchona officinalis
4.1.1.28 L-Tryptophan decarboxylase
-
 Camptotheca acuminata
4.1.1.28 TDC
-
 Solanum lycopersicum
4.1.1.28 TDC
-
 Cinchona calisaya
4.1.1.28 TDC
-
 Catharanthus roseus
4.1.1.28 TDC
-
 Cinchona officinalis
4.1.1.28 TDC
-
 Camptotheca acuminata
4.1.1.28 TDC2
-
 Camptotheca acuminata
4.1.1.28 tryptophan decarboxylase-1
-
 Camptotheca acuminata
4.1.1.28 tryptophan decarboxylase-2
-
 Camptotheca acuminata

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.25 pyridoxal 5'-phosphate
-
 Hordeum vulgare
4.1.1.25 pyridoxal 5'-phosphate
-
 Petroselinum crispum
4.1.1.25 pyridoxal 5'-phosphate
-
 Syringa vulgaris
4.1.1.25 pyridoxal 5'-phosphate
-
 Sanguinaria canadensis
4.1.1.25 pyridoxal 5'-phosphate
-
 Thalictrum rugosum
4.1.1.25 pyridoxal 5'-phosphate
-
 Eschscholzia californica
4.1.1.25 pyridoxal 5'-phosphate
-
 Cytisus scoparius
4.1.1.25 pyridoxal 5'-phosphate
-
 Chondrodendron tomentosum
4.1.1.25 pyridoxal 5'-phosphate
-
 Petunia sp.
4.1.1.25 pyridoxal 5'-phosphate
-
 Arabidopsis thaliana
4.1.1.25 pyridoxal 5'-phosphate
-
 Papaver somniferum
4.1.1.25 pyridoxal 5'-phosphate
-
 Colchicum autumnale
4.1.1.28 pyridoxal 5'-phosphate
-
 Drosophila melanogaster
4.1.1.28 pyridoxal 5'-phosphate
-
 Sus scrofa
4.1.1.28 pyridoxal 5'-phosphate
-
 Solanum lycopersicum
4.1.1.28 pyridoxal 5'-phosphate
-
 Cinchona calisaya
4.1.1.28 pyridoxal 5'-phosphate
-
 Catharanthus roseus
4.1.1.28 pyridoxal 5'-phosphate
-
 Cinchona officinalis
4.1.1.28 pyridoxal 5'-phosphate
-
 Camptotheca acuminata
4.1.1.28 pyridoxal 5'-phosphate
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
4.1.1.28 0.31
-
 tryptamine
-
 Catharanthus roseus

pI Value

EC Number Organism Comment pI Value Maximum pI Value
4.1.1.25 Eschscholzia californica
-
-
 5.2
4.1.1.28 Catharanthus roseus
-
-
 5.9