Literature summary extracted from

Achilles, K.; Schneider, M.; Schirmeister, T.; Otto, H.H.
beta-Lactam derivatives as enzyme inhibitors: N-substituted derivatives of (S)-4-oxoazetidine-2-carboxylate as inhibitors of elastase and papain (2000), Pharmazie, 55, 798-802.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.22.2	(S)-1-[(S)-N-(tert-butyloxycarbonyl)alanyl]-4-oxoazetidine-2-carboxylic acid	weak, irreversible inactivation	Carica papaya
3.4.22.2	benzyl-(S)-1-[(S)-N-(tert-butyloxycarbonyl)alanyl]-4-oxoazetidine-2-carboxylate	weak, irreversible inactivation	Carica papaya
3.4.22.2	benzyl-(S)-2-(benzyloxycarbonyl)azetidin-1-acetate	weak, irreversible inactivation	Carica papaya

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.2	Carica papaya	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.22.2	Nalpha-benzoyl-Arg-p-nitroanilide + H2O	-	Carica papaya	Nalpha-benzoyl-Arg + p-nitroaniline	-	?

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Release 2023.1 (January 2023)