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Literature summary extracted from

  • Poulikakos, P.; Vassilacopoulou, D.; Fragoulis, E.G.
    L-DOPA decarboxylase association with membranes in mouse brain (2001), Neurochem. Res., 26, 479-485.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.1.28 medicine novel approaches in the fight against the pathological conditions that the enzyme is implicated in such as cancer, schizophrenia, psychosis and Parkinson's disease Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.28 cytosol
-
 Mus musculus 5829
-
4.1.1.28 membrane
-
 Mus musculus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.28 50000
-
 SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.28 L-tryptophan Mus musculus
-
 tryptamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.28 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.28 L-Dopa
-
 Mus musculus dopamine + CO2
-
 ?
4.1.1.28 L-tryptophan
-
 Mus musculus tryptamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.28 AADC
-
 Mus musculus
4.1.1.28 aromatic-L-amino-acid decarboxylase
-
 Mus musculus
4.1.1.28 L-DOPA decarboxylase
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.28 pyridoxal 5'-phosphate
-
 Mus musculus