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Literature summary extracted from
- UDP-galactopyranose mutase has a novel structure and mechanism (2001), Nat. Struct. Biol., 8, 858-863.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 5.4.99.9 | overexpression in Escherichia coli | Klebsiella pneumoniae |
| 5.4.99.9 | overexpression in Escherichia coli | Escherichia coli |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 5.4.99.9 | FAD is located in a cleft lined with conserved residues | Escherichia coli |
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 5.4.99.9 | W156A | lower activity than wild-type enzyme | Klebsiella pneumoniae |
| 5.4.99.9 | W156Y | lower activity than wild-type enzyme | Klebsiella pneumoniae |
| 5.4.99.9 | Y151F | lower activity than wild-type enzyme | Klebsiella pneumoniae |
| 5.4.99.9 | Y181F | lower activity than wild-type enzyme | Klebsiella pneumoniae |
| 5.4.99.9 | Y311F | lower activity than wild-type enzyme | Klebsiella pneumoniae |
| 5.4.99.9 | Y346F | lower activity than wild-type enzyme | Klebsiella pneumoniae |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.9 | UDP-galactopyranose | Klebsiella pneumoniae | - |
UDP-galactofuranose | - |
? |  |
| 5.4.99.9 | UDP-galactopyranose | Escherichia coli | - |
UDP-galactofuranose | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.4.99.9 | Escherichia coli | P37747 | - |
- |
| 5.4.99.9 | Klebsiella pneumoniae | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.4.99.9 | - |
Klebsiella pneumoniae |
| 5.4.99.9 | - |
Escherichia coli |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.4.99.9 | UDP-galactopyranose | - |
Klebsiella pneumoniae | UDP-galactofuranose | - |
? | |
| 5.4.99.9 | UDP-galactopyranose | - |
Escherichia coli | UDP-galactofuranose | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.4.99.9 | dimer | solution scattering experiments | Escherichia coli |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 5.4.99.9 | mutase | - |
Klebsiella pneumoniae |
| 5.4.99.9 | mutase | - |
Escherichia coli |
| 5.4.99.9 | UDP-galactopyranose mutase | - |
Klebsiella pneumoniae |
| 5.4.99.9 | UDP-galactopyranose mutase | - |
Escherichia coli |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.4.99.9 | FAD | - |
Klebsiella pneumoniae | |
| 5.4.99.9 | FAD | - |
Escherichia coli | |
| 5.4.99.9 | NAD(P)H | or other reductants | Klebsiella pneumoniae | |
| 5.4.99.9 | NAD(P)H | or other reductants | Escherichia coli | |
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Release 2023.1 (January 2023)
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