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Literature summary extracted from

  • Rhee, M.H.; Nevo, I.; Avidor-Reiss, T.; Levy, R.; Vogel, Z.
    Differential superactivation of adenylyl cyclase isozymes after chronic activation of the CB1 cannabinoid receptor (2000), Mol. Pharmacol., 57, 746-752.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.1 additional information acute activation of cannabinoid receptor 1 leads to stimulation of isoenzymes AC II, AC IV and AC VII Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.6.1.1 expression of isoenzymes ACI-ACVIII in COS cells Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.1 additional information acute activation of cannabinoid receptor 1 leads to inhibition of isoenzymes ACI, AC III, AC VI and AC VIII Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.1 membrane
-
 Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.1 ATP Homo sapiens
-
 3',5'-cyclic AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.1 ATP
-
 Homo sapiens 3',5'-cyclic AMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.1 AC
-
 Homo sapiens
4.6.1.1 adenylyl cyclase
-
 Homo sapiens