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Literature summary extracted from

  • Murray, M.; Greenberg, M.L.
    Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate (2000), Mol. Microbiol., 36, 651-661.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.25 additional information expression is increased in the presence of inositol Saccharomyces cerevisiae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.25 expression in Escherichia coli Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.25 Li+
-
 Saccharomyces cerevisiae
3.1.3.25 additional information Li+, glycerol and glucose in the culture medium depresses enzyme expression, no inhibition with valproate Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.25 31800
-
 calculated from amino acid sequence Saccharomyces cerevisiae
3.1.3.25 32000
-
 SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.25 myo-inositol 1-phosphate + H2O Saccharomyces cerevisiae de novo biosynthesis of inositol, involved in phosphoinositide signaling pathway myo-inositol + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.25 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.25 recombinant protein from Escherichia coli Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.25 additional information no activity with glucose 6-phosphate and 5'-AMP Saccharomyces cerevisiae ?
-
 ?
3.1.3.25 myo-inositol 1,4-bisphosphate + H2O
-
 Saccharomyces cerevisiae ?
-
 ?
3.1.3.25 myo-inositol 1-phosphate + H2O D- and L-isomer serve as substrate Saccharomyces cerevisiae myo-inositol + phosphate
-
 ?
3.1.3.25 myo-inositol 1-phosphate + H2O de novo biosynthesis of inositol, involved in phosphoinositide signaling pathway Saccharomyces cerevisiae myo-inositol + phosphate
-
 ?