EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
6.3.2.3 | additional information | folate and vitamin E depletion leads to 18% increased enzyme expression and activity, mice mutants lacking apolipoprotein E show even higher activation rates of 31% on minimal diet compared to the wild-type on normal diet | Mus musculus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
6.3.2.3 | additional information | ApoE-deficient mice show reduced enzyme expression and activity | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly | Mus musculus | ApoE-deficient mice show reduced enzyme expression and activity, genetic regulation mechanism, overview | ADP + phosphate + glutathione | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.3.2.3 | Mus musculus | - |
normal and ApoE-/- mice | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
6.3.2.3 | partial from brain | Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.3.2.3 | brain | - |
Mus musculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
6.3.2.3 | 3 | 8 | about, wild-type mice on minimal diet | Mus musculus |
6.3.2.3 | 32 | - |
about, ApoE-deficient mice on normal diet | Mus musculus |
6.3.2.3 | 33.5 | - |
about, wild-type mice on normal diet | Mus musculus |
6.3.2.3 | 43 | - |
about, ApoE-deficient mice on minimal diet | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly | - |
Mus musculus | ADP + phosphate + glutathione | - |
? | |
6.3.2.3 | ATP + gamma-L-Glu-L-Cys + Gly | ApoE-deficient mice show reduced enzyme expression and activity, genetic regulation mechanism, overview | Mus musculus | ADP + phosphate + glutathione | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.3.2.3 | GS | - |
Mus musculus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
6.3.2.3 | 37 | - |
assay at | Mus musculus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.3.2.3 | 8 | - |
assay at | Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.3.2.3 | ATP | - |
Mus musculus |