EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.22 | pyruvate | - |
Lactobacillus sp. |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
4.1.1.22 | crystal structure of active HDC at pH 4.8 at 2.5 A resolution, crystal structure of less active HDC at pH 8.0 at 2.7 A resolution, crystals are grown at room temperatur by hanging-drop vapor diffusion, drops contain 0.004 ml HDC at 12.5 mg/ml, 0.001 ml n-dodecyl-beta-D-maltoside and 0.005 ml precipitant solution from the well containing 25% polyethylene glycol 400, 8% polyethylene glycol 400, 100 mM Tris pH 8.0, and 100 mM sodium acetate, enzyme activity is regulated by pH-induced structural changes | Lactobacillus sp. |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.22 | 0.3 | - |
L-histidine | pH 4.8 | Lactobacillus sp. | |
4.1.1.22 | 100 | - |
L-histidine | pH 7.0 | Lactobacillus sp. |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.22 | L-histidine | Lactobacillus sp. | - |
histamine + CO2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.22 | Lactobacillus sp. | P00862 | 30a | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.1.22 | - |
Lactobacillus sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.22 | L-histidine | - |
Lactobacillus sp. | histamine + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
4.1.1.22 | HDC | - |
Lactobacillus sp. |