EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.1.6.8 | crystal structure of mutant C69A a nd C69S in complex with p-nitrocatechol sulfate | Homo sapiens |
3.1.6.8 | crystal structure of mutant C69A in complex with p-nitrocatechol sulfate, Protein Data Bank: 1E1Z and 1E2S, and crystal structure of mutant C69S in complex with p-nitrocatechol sulfate, Protein Data Bank: 1E33 and 1E3C | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.6.8 | C69A | The inactive mutant in complex with p-nitrocatechol sulfate mimics a reaction intermediate during sulfate ester hydrolysis by the active enzyme, without the covalent bond to the key side-chain C-alpha-formylglycine | Homo sapiens |
3.1.6.8 | C69S | the mutant is able to bind covalently to the substrate and hydrolyse it, but is unable to release the resulting sulfate | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.6.8 | cerebroside 3-sulfate + H2O | Homo sapiens | - |
cerebroside + sulfate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.6.8 | Homo sapiens | P15289 | - |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
3.1.6.8 | a cerebroside 3-sulfate + H2O = a cerebroside + sulfate | A detailed mechanism for sulfate ester cleavage is proposed, involving an aldehyde hydrate as the functional group. | Homo sapiens | |
3.1.6.8 | a cerebroside 3-sulfate + H2O = a cerebroside + sulfate | a detailed mechanism for sulfate ester cleavage is proposed, involving an aldehyde hydrate as the functional group | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.6.8 | cerebroside 3-sulfate + H2O | - |
Homo sapiens | cerebroside + sulfate | - |
? | |
3.1.6.8 | p-nitrocatechol sulfate + H2O | - |
Homo sapiens | p-nitrocatechol + sulfate | - |
? |