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Literature summary extracted from

  • Thielens, N.M.; Cseh, S.; Thiel, S.; Vorup-Jensen, T.; Rossi, V.; Jensenius, J.C.; Arlaud, G.J.
    Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL (2001), J. Immunol., 166, 5068-5077.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.B7 expressed in insect or human kidney cells Homo sapiens
3.4.21.104
-
Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.B7 38000
-
calculated molecular mass of the MASP-1 CUB-EGF fragment in the presence of Ca2+ Homo sapiens
3.4.21.B7 58000
-
1 * 58000 + 1 * 30000-32000, SDS-PAGE Homo sapiens
3.4.21.B7 90000
-
proenzyme Homo sapiens
3.4.21.104 29000
-
calculated molecular mass of the MASP-2 CUB-EGF fragment in the presence of Ca2+ Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.B7 additional information Homo sapiens complexes with mannose-binding lectin in the presence of Ca2+, involved in activation of complement cascade ?
-
?
3.4.21.B7 Protein + H2O Homo sapiens
-
?
-
?
3.4.21.104 Protein + H2O Homo sapiens
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.B7 Homo sapiens
-
-
-
3.4.21.104 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.B7 proteolytic modification proenzyme is cleaved between Arg448 and Ile449 Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.B7
-
Homo sapiens
3.4.21.104
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.B7 additional information complexes with mannose-binding lectin in the presence of Ca2+, involved in activation of complement cascade Homo sapiens ?
-
?
3.4.21.B7 Protein + H2O
-
Homo sapiens ?
-
?
3.4.21.104 Protein + H2O
-
Homo sapiens ?
-
?

Subunits

EC Number Subunits Comment Organism
3.4.21.B7 dimer 1 * 58000 + 1 * 30000-32000, SDS-PAGE Homo sapiens
3.4.21.104 dimer homodimer, sedimentation velocity experiments Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.21.B7 MASP-1
-
Homo sapiens
3.4.21.104 MASP-2
-
Homo sapiens