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Literature summary extracted from

  • Sato, T.; Miwa, T.; Akatsu, H.; Matsukawa, N.; Obata, K.; Okada, N.; Campbell, W.; Okada, H.
    Pro-carboxypeptidase R is an acute phase protein in the mouse, whereas carboxypeptidase N is not (2000), J. Immunol., 165, 1053-1058.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.17.3 expression in COS-7 cells Mus musculus
3.4.17.20 procarboxypeptidase R, expression in COS-7 cells Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.3 potato carboxypeptidase inhibitor
-
 Mus musculus
3.4.17.20 potato carboxypeptidase inhibitor
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.3 additional information Mus musculus carboxypeptidase N is not an acute phase protein under inflammatory conditions ?
-
 ?
3.4.17.20 additional information Mus musculus pro-carboxypeptidase R is an acute phase protein under inflammatory conditions ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.3 Mus musculus Q9JJN5
-
-
3.4.17.3 Mus musculus Q9JJN5 carboxypeptidase N, small subunit
-
3.4.17.20 Mus musculus Q9JHH6
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.17.20 proteolytic modification the plasma zymogen pro-carboxypeptidase R is a plasma zymogen activated during coagulation Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.3 liver
-
 Mus musculus
-
3.4.17.3 stomach weak expression Mus musculus
-
3.4.17.20 liver strong expression Mus musculus
-
3.4.17.20 stomach strong expression Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.3 hippuryl-Arg + H2O
-
 Mus musculus hippuric acid + Arg
-
 ?
3.4.17.3 additional information carboxypeptidase N is not an acute phase protein under inflammatory conditions Mus musculus ?
-
 ?
3.4.17.20 hippuryl-Arg + H2O
-
 Mus musculus hippuric acid + Arg
-
 ?
3.4.17.20 additional information pro-carboxypeptidase R is an acute phase protein under inflammatory conditions Mus musculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.3 CPN
-
 Mus musculus
3.4.17.20 Carboxypeptidase R
-
 Mus musculus
3.4.17.20 CPR
-
 Mus musculus