Literature summary extracted from

Chen, L.; Rezaie, A.R.
Proexosite-1-dependent recognition and activation of prothrombin by taipan venom (2004), J. Biol. Chem., 279, 17869-17874.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.21.60	hirudin54-65(SO-3)-	-	Oxyuranus scutellatus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.4.21.60	0.0022	-	prethrombin-1	pH 7.5	Oxyuranus scutellatus
3.4.21.60	0.5	-	prothrombin	pH 7.5	Oxyuranus scutellatus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.4.21.60	50000	-	1 * 50000 + x * ?, catalytically active subunit, SDS-PAGE	Oxyuranus scutellatus
3.4.21.60	220000	-	gel filtration	Oxyuranus scutellatus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.60	Oxyuranus scutellatus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.21.60	partially	Oxyuranus scutellatus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.21.60	prethrombin-1 + H2O	-	Oxyuranus scutellatus	?	-	?
3.4.21.60	prothrombin + H2O	-	Oxyuranus scutellatus	thrombin + ?	-	?

Subunits

EC Number	Subunits	Comment	Organism
3.4.21.60	oligomer	1 * 50000 + x * ?, catalytically active subunit, SDS-PAGE	Oxyuranus scutellatus

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
3.4.21.60	1200	-	prothrombin	pH 7.5	Oxyuranus scutellatus

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Release 2023.1 (January 2023)