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Literature summary extracted from

  • McIlhargey, T.L.; Yang, Y.; Wong, H.; Hill, J.S.
    Identification of a lipoprotein lipase cofactor-binding site by chemical cross-linking and transfer of apolipoprotein C-II-responsive lipolysis from lipoprotein lipase to hepatic lipase (2003), J. Biol. Chem., 278, 23027-23035.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.34 apoprotein C II requirde for activity, approx. 7fold activation, amino acid residues 65-68 and 73-79 of the LPL N-terminal domain appear to act cooperatively to enable substantial activation Bos taurus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.34 expression in HHO cells Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.34 0.0002
-
 triolein
-
 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.34 triacylglycerol + H2O Bos taurus
-
 diacylglycerol + a carboxylate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.34 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.34 recombinant LPL Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.34 triacylglycerol + H2O
-
 Bos taurus diacylglycerol + a carboxylate
-
 ?
3.1.1.34 triolein + H2O
-
 Bos taurus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.34 LPL
-
 Bos taurus