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Literature summary extracted from

  • Zang, X.; Taylor, P.; Wang, J.M.; Meyer, D.J.; Scott, A.L.; Walkinshaw, M.D.; Maizels, R.M.
    Homologues of human macrophage migration inhibitory factor from a parasitic nematode. Gene cloning, protein activity, and crystal structure (2002), J. Biol. Chem., 277, 44261-44267.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.2.1
-
 Brugia malayi

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
5.3.2.1 hanging drop vapor diffusion method, crystal structure of Bm-MIF-2 at 1.8 A resolution reveals a trimeric assembly with an inner pore created by beta-stranded sheets from each subunit Brugia malayi

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.2.1 13100
-
 x * 13100, Bm-MIF-2, calculation from nucleotide sequence Brugia malayi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.2.1 additional information Brugia malayi the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.2.1 Brugia malayi Q9NAS2
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.2.1 additional information the enzyme is chemotactic for human monocytes and activates them to produce IL-8, TNF-alpha and endogenous MIF Brugia malayi ?
-
 ?

Subunits

EC Number Subunits Comment Organism
5.3.2.1 ? x * 13100, Bm-MIF-2, calculation from nucleotide sequence Brugia malayi