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Literature summary extracted from

  • Smith, T.K.; Crossman, A.; Paterson, M.J.; Borissow, C.N.; Brimacombe, J.S.; Ferguson, M.A.J.
    Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in Trypanosoma brucei and HeLa Cells (2002), J. Biol. Chem., 277, 37147-37153.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.89 2-deoxy-2-ureido-D-galactosylalpha1-6-D-myo-inositol-1-phosphoryl-sn-1,2-dipalmitoylglycerol suicide inhibitor, 50% inihibition at 0.0002 mM Trypanosoma brucei
3.5.1.89 2-deoxy-2-ureido-D-glucosylbeta1-6-D-myo-inositol-1-phosphoryl-sn-1,2-dipalmitoylglycerol suicide inhibitor, 50% inihibition at 0.0002 mM Trypanosoma brucei

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.89 Homo sapiens
-
-
-
3.5.1.89 Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.89 additional information structural requirements of substrate, enzyme can act on analogues containing N-benzoyl-, N-acetyl-D-galactosyl- or N-acetyl-beta-D-glucosyl-groups Trypanosoma brucei ?
-
 ?
3.5.1.89 additional information structural requirements of substrate, enzyme cannot act on analogues containing N-benzoyl-, N-acetyl-D-galactosyl- or N-acetyl-beta-D-glucosyl-groups Homo sapiens ?
-
 ?