Literature summary extracted from

Phillips, R.S.; Demidkina, T.V.; Zakomirdina, L.N.; Bruno, S.; Ronda, L.; Mozzarelli, A.
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes (2002), J. Biol. Chem., 277, 21592-21597.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
4.1.99.1	in complex with oxindolyl-L-alanine and with L-tryptophan and L-serine	Proteus vulgaris
4.1.99.2	in complex with L-methionine and L-phenylalanine, wild type and mutant Y71F	Citrobacter freundii

Protein Variants

EC Number	Protein Variants	Comment	Organism
4.1.99.2	Y71F	no enzymic activity, crystallization data	Citrobacter freundii

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.99.1	Proteus vulgaris	-	-	-
4.1.99.2	Citrobacter freundii	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
4.1.99.1	L-tryptophan + H2O = indole + pyruvate + NH3	mechanism	Proteus vulgaris	a
4.1.99.2	L-tyrosine + H2O = phenol + pyruvate + NH3	mechanism	Citrobacter freundii	a

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Release 2023.1 (January 2023)