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Literature summary extracted from

  • Saric, T.; Beninga, J.; Graef, C.I.; Akopian, T.N.; Rock, K.L.; Goldberg, A.L.
    Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase (2001), J. Biol. Chem., 276, 36474-36481.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.15 cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.15 major histocompatibility complex class I-presented antigenic peptides + H2O Homo sapiens by destroying major histocompatibility complex class I-presented antigenic peptides the enzyme limits antigen presentation in vivo ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.15 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.15 HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.15 ASNENMETM + H2O
-
Homo sapiens ?
-
?
3.4.24.15 FAPGNYPAL + H2O
-
Homo sapiens ?
-
?
3.4.24.15 major histocompatibility complex class I-presented antigenic peptides + H2O by destroying major histocompatibility complex class I-presented antigenic peptides the enzyme limits antigen presentation in vivo Homo sapiens ?
-
?
3.4.24.15 RGPGRAFVTI + H2O
-
Homo sapiens ?
-
?
3.4.24.15 SIINFEKL + H2O
-
Homo sapiens ?
-
?
3.4.24.15 TPHPARIGL + H2O
-
Homo sapiens ?
-
?
3.4.24.15 TYQRTRALV + H2O
-
Homo sapiens ?
-
?