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Literature summary extracted from
- Stoichiometry of complexes between mannose-binding protein and its associated serine proteases. Defining functional units for complement activation (2001), J. Biol. Chem., 276, 25894-25902.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.21.B7 | expressed in CHO cells | Homo sapiens |
| 3.4.21.104 | expressed in CHO cells | Homo sapiens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.B7 | 65000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.B7 | additional information | Homo sapiens | involved in activation of complement cascade, smallest functional unit for complement activation consists of serum mannose-binding protein dimers bound to MASP-1 homodimers | ? | - |
? |  |
| 3.4.21.B7 | Protein + H2O | Homo sapiens | - |
? | - |
? | |
| 3.4.21.104 | additional information | Homo sapiens | smallest functional unit for complement activation consists of mannose-binding protein dimers bound to MASP-2 homodimers | ? | - |
? | |
| 3.4.21.104 | Protein + H2O | Homo sapiens | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.B7 | Homo sapiens | - |
- |
- |
| 3.4.21.104 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.21.B7 | glycoprotein | - |
Homo sapiens |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.B7 | - |
Homo sapiens |
| 3.4.21.104 | - |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.B7 | additional information | involved in activation of complement cascade, smallest functional unit for complement activation consists of serum mannose-binding protein dimers bound to MASP-1 homodimers | Homo sapiens | ? | - |
? | |
| 3.4.21.B7 | Protein + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.104 | additional information | smallest functional unit for complement activation consists of mannose-binding protein dimers bound to MASP-2 homodimers | Homo sapiens | ? | - |
? | |
| 3.4.21.104 | Protein + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.B7 | MASP-1 | - |
Homo sapiens |
| 3.4.21.104 | MASP-2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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