EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.24.B4 | overexpression in Escherichia coli BL21(DE3) | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.24.B4 | matrix metalloprotease inhibitor GW9471 | broad spectrum | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B4 | protein + H2O | Homo sapiens | - |
peptides | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.24.B4 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.24.B4 | recombinant refolded enzyme form Escherichia coli | Homo sapiens |
EC Number | Renatured (Comment) | Organism |
---|---|---|
3.4.24.B4 | recombinant enzyme form inclusion bodies after expression in Escherichia coli | Homo sapiens |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.24.B4 | additional information | - |
substrate specificity | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.24.B4 | 2,4-dinitrophenyl-GPLGMRGL-NH2 + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.24.B4 | aggrecan + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.24.B4 | alpha2-chain of type IV collagen + H2O | cleavage sites at amino acid residues 881 and 1000 in the triple-helical region | Homo sapiens | ? | - |
? | |
3.4.24.B4 | alpha4-chain of type IV collagen + H2O | cleavage site at amino acid residue 86 in the triple-helical region | Homo sapiens | ? | - |
? | |
3.4.24.B4 | protein + H2O | - |
Homo sapiens | peptides | - |
? | |
3.4.24.B4 | protein + H2O | substrate specificity and cleavage site determination via phage display approach | Homo sapiens | peptides | - |
? | |
3.4.24.B4 | Transforming growth factor + H2O | cleavage site at amino acid residue 150 in the latency-associated peptide | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.24.B4 | M10.013 | Merops-ID | Homo sapiens |
3.4.24.B4 | matrix metalloproteinase-13 | - |
Homo sapiens |
3.4.24.B4 | MMP-13 | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.24.B4 | 0.0000005 | - |
matrix metalloprotease inhibitor GW9471 | 37°C, recombinant enzyme | Homo sapiens |