BRENDA - Enzyme Database

A developmentally regulated aconitase related to iron-regulatory protein-1 is localized in the cytoplasm and in the mitochondrion of Trypanosoma brucei

Saas, J.; Ziegelbauer, K.; von Haeseler, A.; Fast, B.; Boshart, M.; J. Biol. Chem. 275, 2745-2755 (2000)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
4.2.1.3
expression in Escherichia coli
Trypanosoma brucei
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.2.1.3
3
-
isocitrate
recombinant enzyme
Trypanosoma brucei
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.3
cytoplasm
-
Trypanosoma brucei
5737
-
4.2.1.3
mitochondrion
-
Trypanosoma brucei
5739
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.3
additional information
Trypanosoma brucei
the enzyme does not take part in the mitochondrial Krebs cycle but may have a yet unknown function in the cytoplasm of the parasite
?
-
Trypanosoma brucei
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.3
Trypanosoma brucei
Q9NJQ8
3'-untranslated region; fragment
-
4.2.1.3
Trypanosoma brucei
Q9NJQ9
fragment
-
Purification (Commentary)
EC Number
Commentary
Organism
4.2.1.3
-
Trypanosoma brucei
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.3
isocitrate
-
652036
Trypanosoma brucei
?
-
652036
Trypanosoma brucei
?
4.2.1.3
additional information
the enzyme does not take part in the mitochondrial Krebs cycle but may have a yet unknown function in the cytoplasm of the parasite
652036
Trypanosoma brucei
?
-
652036
Trypanosoma brucei
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
4.2.1.3
expression in Escherichia coli
Trypanosoma brucei
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.2.1.3
3
-
isocitrate
recombinant enzyme
Trypanosoma brucei
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
4.2.1.3
cytoplasm
-
Trypanosoma brucei
5737
-
4.2.1.3
mitochondrion
-
Trypanosoma brucei
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.2.1.3
additional information
Trypanosoma brucei
the enzyme does not take part in the mitochondrial Krebs cycle but may have a yet unknown function in the cytoplasm of the parasite
?
-
Trypanosoma brucei
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.2.1.3
-
Trypanosoma brucei
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.3
isocitrate
-
652036
Trypanosoma brucei
?
-
652036
Trypanosoma brucei
?
4.2.1.3
additional information
the enzyme does not take part in the mitochondrial Krebs cycle but may have a yet unknown function in the cytoplasm of the parasite
652036
Trypanosoma brucei
?
-
652036
Trypanosoma brucei
?