Any feedback?
Literature summary extracted from
- Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment (2000), J. Biol. Chem., 275, 2349-2358.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.21.112 | - |
Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.112 | 1,10-phenanthroline | complete inactivation at 5 mM | Homo sapiens |  |
| 3.4.21.112 | CuSO4 | complete inactivation at 1 mM | Homo sapiens | |
| 3.4.21.112 | EDTA | complete inactivation at 10 mM | Homo sapiens | |
| 3.4.21.112 | EGTA | 85% inactivation at 10 mM | Homo sapiens | |
| 3.4.21.112 | prosegment of SKI-1 | - |
Homo sapiens | |
| 3.4.21.112 | ZnSO4 | complete inactivation at 1 mM | Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.112 | Ca2+ | dependent | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.112 | 98000 | - |
SDS-PAGE | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.112 | Homo sapiens | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.21.112 | glycoprotein | putative N-glycosylation at Asn148 | Homo sapiens |
| 3.4.21.112 | proteolytic modification | proSKI-1 is converted to active SKI-1 | Homo sapiens |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.112 | - |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.112 | additional information | peptides containing RSLK and RRLL are cleaved best | Homo sapiens | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.112 | hSKI-1 | - |
Homo sapiens |
| 3.4.21.112 | SKI-1/S1P | - |
Homo sapiens |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.112 | 6.5 | - |
- |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
