EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.B28 | - |
Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.4.21.B28 | S624A | inactive mutant | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.B28 | diisopropylfluorophosphate | 50% inhibition at 0.02 mM | Homo sapiens | |
3.4.21.B28 | phenylmethylsulfonyl fluoride | 50% inhibition at 0.1 mM | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.B28 | 0.46 | - |
Ala-Pro-4-trifluoromethylcoumarin-7-amide | pH 7.8, 37°C | Homo sapiens | |
3.4.21.B28 | 0.9 | - |
Lys-Pro-4-trifluoromethylcoumarin-7-amide | pH 7.8, 37°C | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.21.B28 | 215000 | - |
SDS-PAGE under nonreducing conditions | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.B28 | Type I collagen + H2O | Homo sapiens | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.B28 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.B28 | fibroblast | reactive tumor stromal fibroblast and granulation tissue during wound healing | Homo sapiens | - |
3.4.21.B28 | additional information | no activity in normal adult human tissues | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.B28 | Ala-Pro-4-trifluoromethylcoumarin-7-amide + H2O | - |
Homo sapiens | Ala-Pro + 7-amino-4-trifluoromethylcoumarin | - |
? | |
3.4.21.B28 | Gelatin + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.B28 | Lys-Pro-4-trifluoromethylcoumarin-7-amide + H2O | - |
Homo sapiens | Lys-Pro + 7-amino-4-trifluoromethylcoumarin | - |
? | |
3.4.21.B28 | Type I collagen + H2O | - |
Homo sapiens | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.21.B28 | dimer | - |
Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.B28 | FAP | - |
Homo sapiens |
3.4.21.B28 | seprase | - |
Homo sapiens |