Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Norcum, M.T.; Dignam, J.D.
    Immunoelectron microscopic localization of glutamyl-/prolyl-tRNA synthetase within the eukaryotic multisynthetase complex (1999), J. Biol. Chem., 274, 12205-12208.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.15 ATP + L-proline + tRNAPro Oryctolagus cuniculus
-
 AMP + diphosphate + L-prolyl-tRNAPro
-
 ?
6.1.1.17 ATP + L-glutamate + tRNAGlu Oryctolagus cuniculus
-
 AMP + diphosphate + L-glutamyl-tRNAGlu
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.15 Oryctolagus cuniculus
-
 purified multisynthetase complex, the enzyme is a bifunctional glutamyl-/prolyl-tRNA synthetase
-
6.1.1.17 Oryctolagus cuniculus
-
 enzyme has dual substrate specificity for L-glutamate and L-proline, enzyme is part of a large aminoacyl-tRNA synthetases complex
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.1.1.17 reticulocyte
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.15 ATP + L-proline + tRNAPro
-
 Oryctolagus cuniculus AMP + diphosphate + L-prolyl-tRNAPro
-
 ?
6.1.1.17 ATP + L-glutamate + tRNAGlu
-
 Oryctolagus cuniculus AMP + diphosphate + L-glutamyl-tRNAGlu
-
 ?
6.1.1.17 ATP + L-glutamate + tRNAGlu enzyme has dual substrate specificity for L-glutamate and L-proline Oryctolagus cuniculus AMP + diphosphate + L-glutamyl-tRNAGlu
-
 ?
6.1.1.17 ATP + L-proline + tRNAGlu enzyme has dual substrate specificity for L-glutamate and L-proline Oryctolagus cuniculus AMP + diphosphate + L-prolyl-tRNAGlu
-
 ?

Subunits

EC Number Subunits Comment Organism
6.1.1.15 dimer bifunctional enzyme Oryctolagus cuniculus
6.1.1.15 More multienzyme complex organization and structure by visualization of immunologically stained sites Oryctolagus cuniculus
6.1.1.17 More structure and organization of the multienzyme complex Oryctolagus cuniculus

Synonyms

EC Number Synonyms Comment Organism
6.1.1.15 Global RNA synthesis factor
-
 Oryctolagus cuniculus
6.1.1.15 GluProRS
-
 Oryctolagus cuniculus
6.1.1.15 glutamyl-/prolyl-tRNA synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Pro-tRNA synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Proline translase
-
 Oryctolagus cuniculus
6.1.1.15 Proline--tRNA ligase
-
 Oryctolagus cuniculus
6.1.1.15 Prolyl RNA synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Prolyl-transfer ribonucleate synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Prolyl-transfer ribonucleic acid synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Prolyl-transfer RNA synthetase
-
 Oryctolagus cuniculus
6.1.1.15 Prolyl-tRNA synthetase
-
 Oryctolagus cuniculus
6.1.1.15 ProRS
-
 Oryctolagus cuniculus
6.1.1.17 Glutamyl-tRNA synthetase
-
 Oryctolagus cuniculus

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.15 ATP
-
 Oryctolagus cuniculus
6.1.1.17 ATP
-
 Oryctolagus cuniculus