EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.5 | ethyl monate-A | - |
Staphylococcus aureus | |
6.1.1.5 | Ile-NHSO2-AMP | non-hydrolyzable reaction intermediate analogue, slow-tight binding, competitive and inhibition mechanism, reversible | Staphylococcus aureus | |
6.1.1.5 | isoleucinyl-adenylate | i.e. Ile-ol-AMP, non-hydrolyzable reaction intermediate analogue, slow-tight binding, competitive and inhibition mechanism, reversible | Staphylococcus aureus | |
6.1.1.5 | pseudomonic acid | forms a non-hydrolyzable reaction intermediate analogue, competitive inhibition | Staphylococcus aureus | |
6.1.1.5 | SB-205952 | a semisynthetic analogue of monic acid, possesing a nitrofuryl chromophore | Staphylococcus aureus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.5 | ATP + L-isoleucine + tRNAIle | Staphylococcus aureus | - |
AMP + diphosphate + L-isoleucyl-tRNAIle | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.1.1.5 | Staphylococcus aureus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.1.1.5 | ATP + L-isoleucine + tRNAIle | - |
Staphylococcus aureus | AMP + diphosphate + L-isoleucyl-tRNAIle | - |
r | |
6.1.1.5 | additional information | enzyme also performs the reversible ATP-diphosphate exchange reaction | Staphylococcus aureus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.1.1.5 | IleRS | - |
Staphylococcus aureus |
6.1.1.5 | IRS | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucine translase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucine--tRNA ligase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucine-transfer RNA ligase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucine-tRNA synthetase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucyl-transfer ribonucleate synthetase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucyl-transfer RNA synthetase | - |
Staphylococcus aureus |
6.1.1.5 | Isoleucyl-tRNA synthetase | - |
Staphylococcus aureus |
6.1.1.5 | Mupirocin resistance protein | - |
Staphylococcus aureus |
6.1.1.5 | Synthetase, isoleucyl-transfer ribonucleate | - |
Staphylococcus aureus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
6.1.1.5 | 22 | - |
assay at | Staphylococcus aureus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.1.1.5 | 7.9 | - |
assay at | Staphylococcus aureus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.1.1.5 | ATP | - |
Staphylococcus aureus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
6.1.1.5 | additional information | - |
additional information | inhibition kinetics | Staphylococcus aureus | |
6.1.1.5 | 0.000003 | - |
Ile-NHSO2-AMP | pH 7.9, 22°C | Staphylococcus aureus | |
6.1.1.5 | 0.00002 | - |
pseudomonic acid | pH 7.9, 22°C | Staphylococcus aureus | |
6.1.1.5 | 0.00004 | - |
ethyl monate-A | pH 7.9, 22°C | Staphylococcus aureus | |
6.1.1.5 | 0.000045 | - |
SB-205952 | pH 7.9, 22°C | Staphylococcus aureus | |
6.1.1.5 | 0.00009 | - |
isoleucinyl-adenylate | pH 7.9, 22°C | Staphylococcus aureus |