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Literature summary extracted from

  • Johnson, J.D.; Muhonen, W.W.; Lambeth, D.O.
    Characterization of the ATP- and GTP-specific succinyl-CoA synthetases in pigeon. The enzymes incorporate the same alpha-subunit (1998), J. Biol. Chem., 273, 27573-27579.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.4 0.007
-
 GDP pH 8.0, 30°C Pigeon
6.2.1.4 0.036
-
 CoA pH 8.0, 30°C Pigeon
6.2.1.4 0.036
-
 GTP pH 8.0, 30°C Pigeon
6.2.1.4 0.086
-
 succinyl-CoA pH 8.0, 30°C Pigeon
6.2.1.4 0.49
-
 succinate pH 8.0, 30°C Pigeon
6.2.1.4 2.26
-
 phosphate pH 8.0, 30°C Pigeon
6.2.1.5 0.032
-
 CoA pH 8.0, 30°C Columba livia
6.2.1.5 0.041
-
 succinyl-CoA pH 8.0, 30°C Columba livia
6.2.1.5 0.055
-
 ATP pH 8.0, 30°C Columba livia
6.2.1.5 0.25
-
 ADP pH 8.0, 30°C Columba livia
6.2.1.5 0.72
-
 phosphate pH 8.0, 30°C Columba livia
6.2.1.5 5.1
-
 succinate pH 8.0, 30°C Columba livia

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.2.1.4 35000
-
 alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Pigeon
6.2.1.4 44500
-
 alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Pigeon
6.2.1.5 35000
-
 alphaxbetay, x * 35000 + y * 42500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Columba livia
6.2.1.5 42500
-
 alphaxbetay, x * 35000 + y * 42500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Columba livia

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.4 Pigeon
-
-
-
6.2.1.5 Columba livia
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.2.1.4
-
 Pigeon
6.2.1.5
-
 Columba livia

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.4 liver
-
 Pigeon
-
6.2.1.5 breast muscle
-
 Columba livia
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.2.1.4 22.1
-
-
 Pigeon
6.2.1.5 6.61
-
-
 Columba livia

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.4 GTP + succinate + CoA
-
 Pigeon GDP + phosphate + succinyl-CoA
-
 r
6.2.1.5 ATP + succinate + CoA
-
 Columba livia ADP + phosphate + succinyl-CoA
-
 r

Subunits

EC Number Subunits Comment Organism
6.2.1.4 ? alphaxbetay, x * 35000 + y * 44500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Pigeon
6.2.1.5 ? alphaxbetay, x * 35000 + y * 42500, ATP-specific succinyl-CoA synthetase and GTP-specific succinyl-CoA synthetase incorporate the same alpha-subunit, SDS-PAGE Columba livia

Synonyms

EC Number Synonyms Comment Organism
6.2.1.4 G-SCS
-
 Pigeon
6.2.1.5 A-SCS
-
 Columba livia

pI Value

EC Number Organism Comment pI Value Maximum pI Value
6.2.1.4 Pigeon isoelectric focusing 7.4 7.3
6.2.1.5 Columba livia isoelectric focusing
-
 7.9