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Literature summary extracted from

  • Deng, K.; Zhang, L.; Kachurin, A.M.; Yu, L.; Xia, D.; Kim, H.; Deisenhofer, J.; Yu, C.A.
    Activation of a matrix processing peptidase from the crystalline cytochrome bc1 complex of bovine heart mitochondria (1998), J. Biol. Chem., 273, 20752-20757.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.24.64 Triton X-100
-
 Bos taurus

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.24.64 crystalline cytochrome bc1 complex Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.64 dithiothreitol partial, 81% inhibition Bos taurus
3.4.24.64 EDTA
-
 Bos taurus
3.4.24.64 ferricyanide partial, 28% inhibition Bos taurus
3.4.24.64 additional information antimycin, phenylmethylsulfonyl fluoride, hemin, pepstatin, and N-ethylmaleimide are no inhibitors Bos taurus
3.4.24.64 Myxothiazol partial, 58% inhibition Bos taurus
3.4.24.64 o-phenanthroline
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.64 mitochondrion
-
 Bos taurus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.64 Co2+ divalent cation required for enzyme activity Bos taurus
3.4.24.64 Fe2+ divalent cation required for enzyme activity Bos taurus
3.4.24.64 Mg2+ divalent cation required for enzyme activity Bos taurus
3.4.24.64 Mn2+ divalent cation required for enzyme activity Bos taurus
3.4.24.64 Zn2+ divalent cation required for enzyme activity Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.64 Bos taurus
-
 bovine, beef
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.64 cytochrome bc1 complex Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.64 ALQPARDYAAQASPSPKA + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 ALQPARDYAAQASPSPKAGATTGRIVAV + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 ASVRYSHTDIKVPDFSDYRRPEVLD + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 AVALHSAVSASDLELHPPSY + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 AVALHSAVSASDLELHPPSYPWSHRGLLSS + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 RPLVASVSLNVPASVRYSHTDIKVPDF + H2O
-
 Bos taurus ?
-
 ?
3.4.24.64 VPASVRYSHTDIK + H2O
-
 Bos taurus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.64 MPP
-
 Bos taurus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.24.64 37
-
-
 Bos taurus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.24.64 42
-
 drastic decrease in activity, activated enzyme is unstable and becomes partially denatured Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.64 6.5 8.5
-
 Bos taurus