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Literature summary extracted from

  • Noh, H.J.; Kwon, S.J.; Kim, K.T.; Lee, C.H.; Yoon, M.Y.
    Allosteric properties of Hafnia alvei aspartase by nucleotide effectors (2000), J. Biochem. Mol. Biol., 33, 366-369.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.3.1.1 adenosine activation to 120-130%, allosteric Hafnia alvei
4.3.1.1 AMP allosteric activation, restores original activity of trypsin-treated enzyme Hafnia alvei
4.3.1.1 GTP allosteric activation, restores original activity of trypsin-treated enzyme Hafnia alvei
4.3.1.1 guanosine activation to 120-130%, allosteric Hafnia alvei

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.1 CTP allosteric inhibition, moderate decrease in activity Hafnia alvei
4.3.1.1 cytidine allosteric inhibition, moderate decrease in activity Hafnia alvei

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.1 Hafnia alvei
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