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Literature summary extracted from

  • O'Toole, G.A.; Escalante-Semerena, J.C.
    cobU-dependent assimilation of nonadenosylated cobinamide in cobA mutants of Salmonella typhimurium (1993), J. Bacteriol., 175, 6328-6336.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.156 overexpressed Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.62 overexpressed Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.156 ATP + adenosylcobinamide Salmonella enterica subsp. enterica serovar Typhimurium cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 adenosylcobinamide phosphate + ADP
-
 ?
2.7.1.156 GTP + adenosylcobinamide Salmonella enterica subsp. enterica serovar Typhimurium
-
 adenosylcobinamide phosphate + GDP
-
 ?
2.7.7.62 GTP + adenosylcobinamide phosphate Salmonella enterica subsp. enterica serovar Typhimurium cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 diphosphate + adenosylcobinamide-GDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.156 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
2.7.7.62 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.156 ATP + adenosylcobinamide
-
 Salmonella enterica subsp. enterica serovar Typhimurium adenosylcobinamide phosphate + ADP
-
 ?
2.7.1.156 ATP + adenosylcobinamide cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Salmonella enterica subsp. enterica serovar Typhimurium adenosylcobinamide phosphate + ADP
-
 ?
2.7.1.156 GTP + adenosylcobinamide
-
 Salmonella enterica subsp. enterica serovar Typhimurium adenosylcobinamide phosphate + GDP
-
 ?
2.7.7.62 GTP + adenosylcobinamide phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + adenosylcobinamide-GDP
-
 ?
2.7.7.62 GTP + adenosylcobinamide phosphate cobalamin biosynthesis, involved in de novo synthesis of vitamin B12 Salmonella enterica subsp. enterica serovar Typhimurium diphosphate + adenosylcobinamide-GDP
-
 ?
2.7.7.62 additional information CobU is a bifunctional enzyme that has both kinase EC 2.7.1.156 and guanyltransferase EC 2.7.7.62 activities Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.156 CobU
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.1.156 CobU protein
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.62 CobU
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.7.62 CobU protein
-
 Salmonella enterica subsp. enterica serovar Typhimurium