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Literature summary extracted from

  • Batten, M.R.; Senior, B.W.; Kilian, M.; Woof, J.M.
    Amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by streptococcal IgA1 proteases (2003), Infect. Immun., 71, 1462-1469.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.13 Streptococcus mitis
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strains: SK564, SK597 and SK599
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3.4.24.13 Streptococcus oralis
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-
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3.4.24.13 Streptococcus pneumoniae
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-
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3.4.24.13 Streptococcus sanguinis
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strains: SK1, SK4 and SK49
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.13 Immunoglobulin A1 + H2O amino acid sequence requirements in the hinge of human immunoglobulin A1. Absolute requirement for Pro227 but not for Thr228, which can be replaced by Val Streptococcus sanguinis ?
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?
3.4.24.13 Immunoglobulin A1 + H2O amino acid sequence requirements in the hinge of human immunoglobulin A1. Absolute requirement for Pro227 but not for Thr228, which can be replaced by Val Streptococcus oralis ?
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?
3.4.24.13 Immunoglobulin A1 + H2O amino acid sequence requirements in the hinge of human immunoglobulin A1. Absolute requirement for Pro227 but not for Thr228, which can be replaced by Val. Enzyme from different strains may have different amino acid requirements for cleavage Streptococcus mitis ?
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?
3.4.24.13 Immunoglobulin A1 + H2O amino acid sequence requirements in the hinge of human immunoglobulin A1. The enzyme shows no absolute requirement for either Pro or Thr at residue 227 to 228 Streptococcus pneumoniae ?
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?