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Literature summary extracted from

  • Flieger, A.; Neumeister, B.; Cianciotto, N.P.
    Characterization of the gene encoding the major secreted lysophospholipase A of Legionella pneumophila and its role in detoxification of lysophosphatidylcholine (2002), Infect. Immun., 70, 6094-6106.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.5 expression in Escherichia coli, overexpression in Legionella pneumophila completely protects from the toxic effects of lysophosphatidylcholine Legionella pneumophila

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.5 extracellular major secreted lysophospholipase A Legionella pneumophila
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.5 1-monopalmitoyllysophosphatidylglycerol + H2O Legionella pneumophila
-
 glycerophosphoglycerol + palmitic acid
-
 ?
3.1.1.5 1-palmitoyl-sn-glycero-3-phosphocholine + H2O Legionella pneumophila
-
 glycerophosphocholine + palmitate
-
 ?
3.1.1.5 2-lysophosphatidylcholine + H2O Legionella pneumophila
-
 glycerophosphocholine + a carboxylate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.5 Legionella pneumophila Q8GNM7
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.5 1-monopalmitoyllysophosphatidylglycerol + H2O
-
 Legionella pneumophila glycerophosphoglycerol + palmitic acid
-
 ?
3.1.1.5 1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Legionella pneumophila glycerophosphocholine + palmitate
-
 ?
3.1.1.5 2-lysophosphatidylcholine + H2O
-
 Legionella pneumophila glycerophosphocholine + a carboxylate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.5 lysophospholipase A
-
 Legionella pneumophila
3.1.1.5 plaA
-
 Legionella pneumophila