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Literature summary extracted from

  • Salonen, T.; Jarvela, I.; Peltonen, L.; Jalanko, A.
    Detection of eight novel palmitoyl protein thioesterase (PPT) mutations underlying infantile neuronal ceroid lipofuscinosis (INCL;CLN1) (2000), Hum. Mutat., 15, 273-279.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.2.22 gene ppt, DNA sequence determnation and analysis, identification of 8 natural mutations of different origins leading to enzyme deficiency Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.2.22 additional information Homo sapiens enzyme deficiency causes the infantile form of neuronal ceroid lipofuscinosis INCL, a progressive encephalopathyof children ?
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?

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.22 Homo sapiens
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-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.2.22 palmitoyl[protein] + H2O = palmitate + protein specific for long-chain thioesters of fatty acids from S-acylated residues in proteins, palmitoyl cysteine and palmitoyl-CoA Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.22 additional information enzyme deficiency causes the infantile form of neuronal ceroid lipofuscinosis INCL, a progressive encephalopathyof children Homo sapiens ?
-
?
3.1.2.22 palmitoyl-[protein] + H2O
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Homo sapiens palmitate + protein
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?

Synonyms

EC Number Synonyms Comment Organism
3.1.2.22 palmitoyl protein thioesterase
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Homo sapiens
3.1.2.22 PPT
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Homo sapiens