EC Number | Application | Comment | Organism |
---|---|---|---|
3.1.6.4 | medicine | enzyme defect leads to mucopolysaccharidosis IVA | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.6.4 | expressed in deficient fibroblasts | Homo sapiens |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.6.4 | C79S | no enzymatic activity | Homo sapiens |
3.1.6.4 | C79T | no enzymatic activity | Homo sapiens |
3.1.6.4 | F97V | 10fold decrease in enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | G155R | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | G301C | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | I113F | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | N204K | decreased enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | P125L | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | P151L | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | P77R | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | R295Q | decreased enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | R386C | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | R94C | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | R94G | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | S162F | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | T312S | decreased enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
3.1.6.4 | V138A | no enzymatic activity, no mature polypeptide chain and precursor polypeptide is faintly visible | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.6.4 | 40000 | - |
mature protein, SDS-PAGE | Homo sapiens |
3.1.6.4 | 52000 | 53000 | N204K mutant, precursor protein lacking one carbohydrate chain, SDS-PAGE | Homo sapiens |
3.1.6.4 | 55000 | - |
precursor protein, SDS-PAGE | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.6.4 | Homo sapiens | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.1.6.4 | glycoprotein | one carbohydrate chain per subunit | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.6.4 | Gal(6-SO4)beta(1-4)-GlcAc(6-SO4)beta(1-4)-D-galactitol + H2O | - |
Homo sapiens | sulfate + ? | - |
? | |
3.1.6.4 | galactose 6-sulfate + H2O | in chondroitin sulfate or keratan sulfate | Homo sapiens | galactose + sulfate | - |
? |