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Literature summary extracted from

  • Arai, S.; Allan, C.; Streiff, M.; Hutchins, G.M.; Vogelsang, G.B.; Tsai, H.M.
    Von Willebrand factor-cleaving protease activity and proteolysis of von Willebrand factor in bone marrow transplant-associated thrombotic microangiopathy (2001), Hematol. J., 2, 292-299.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.24.87 medicine analysis of vWF protease and vWF multimeric distribution are valuable tools in making the distinction between bone marrow transplant-associated thrombotid microangiopathy and thrombotic thrombocytopenic pupura Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.87 EDTA
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.87 extracellular plasma Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.87 proteins + H2O Homo sapiens
-
 peptides
-
 ?
3.4.24.87 von Willebrand factor + H2O Homo sapiens decrease of the multimeric pattern of enzyme and decreased activity results in bone marrow transplant-associated thrombotid microangiopathy ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.87 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.87 kidney
-
 Homo sapiens
-
3.4.24.87 plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.87 proteins + H2O
-
 Homo sapiens peptides
-
 ?
3.4.24.87 von Willebrand factor + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.87 von Willebrand factor + H2O decrease of the multimeric pattern of enzyme and decreased activity results in bone marrow transplant-associated thrombotid microangiopathy Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.87 M12.241 Merops-ID Homo sapiens
3.4.24.87 von Willebrand factor-cleaving protease
-
 Homo sapiens
3.4.24.87 vWF protease
-
 Homo sapiens