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Literature summary extracted from
- Extremely rapid turnover of S-adenosylmethionine decarboxylase in Crithidia fasciculata (2003), FEBS Lett., 553, 131-134.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.50 | putrescine | strong | Crithidia fasciculata |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.50 | methylglyoxal-bis(guanylhydrazone) | 50% inhibition at 0.012 mM | Crithidia fasciculata | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.50 | 0.2 | - |
S-adenosyl-L-methionine | pH 7.5, 28 | Crithidia fasciculata | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.50 | Crithidia fasciculata | - |
increase in enzyme activity during exponential growth | - |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 4.1.1.50 | additional information | half-life of enzyme is about 3 min | Crithidia fasciculata |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.50 | S-adenosyl-L-methionine | - |
Crithidia fasciculata | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
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Release 2023.1 (January 2023)
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