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Literature summary extracted from

  • Nagai, K.; Niijima, A.; Yamano, T.; Otani, H.; Okumra, N.; Tsuruoka, N.; Nakai, M.; Kiso, Y.
    Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves (2003), Exp. Biol. Med., 228, 1138-1145.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.11 L-histidine + beta-alanine + ATP Rattus norvegicus
-
 carnosine + AMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.11 Rattus norvegicus
-
 male Winstar rats
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.2.11 partial, using ammonium sulfate precipitation Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.3.2.11 muscle
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.3.2.11 additional information
-
 activity in muscle is higher after exercise, which may lead to an increase of the L-carnosine levels in plasma Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.11 L-histidine + beta-alanine + ATP
-
 Rattus norvegicus carnosine + AMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.2.11 Carnosine synthetase
-
 Rattus norvegicus
6.3.2.11 Carnosine-anserine synthetase
-
 Rattus norvegicus
6.3.2.11 Carnosine-homocarnosine synthetase
-
 Rattus norvegicus
6.3.2.11 Homocarnosine-carnosine synthetase
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.3.2.11 37
-
 assay at Rattus norvegicus