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Literature summary extracted from

  • Seifert, C.; Bowien, S.; Gottschalk, G.; Daniel, R.
    Identification and expression of the genes and purification and characterization of the gene products involved in reactivation of coenzyme B12-dependent glycerol dehydratase of Citrobacter freundii (2001), Eur. J. Biochem., 268, 2369-2378.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.2.1.30 DhaF formerly OrfZ, DhaF-DhaG alpha2beta2 complex rapidly reactivates glycerol-or O2-inactivated hologlycerol dehydratase and activates the enzyme cyanocobalamin complex in the presence of coenzyme B12, ATP and Mg2+ Citrobacter freundii
4.2.1.30 DhaG formerly OrfX, DhaF-DhaG alpha2beta2 complex rapidly reactivates glycerol-or O2-inactivated hologlycerol dehydratase and activates the enzyme cyanocobalamin complex in the presence of coenzyme B12, ATP and Mg2+ Citrobacter freundii

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.30 glycerol suicide inactivation, 65% activity after 3 min, 3% activity after 30 min Citrobacter freundii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.30 glycerol Citrobacter freundii
-
 3-hydroxypropanal + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.30 Citrobacter freundii
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.30 glycerol
-
 Citrobacter freundii 3-hydroxypropanal + H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.2.1.30 37
-
 assay at Citrobacter freundii