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Literature summary extracted from

  • Chaufan, G.; Corvi, M.; Armesto, A.; San Martin de Viale, L.C.; Luquet, C.; Rios de Molina, M.
    Comparison between crab hepatopancreas and rat liver uroporphyrinogen decarboxylase (2002), Comp. Biochem. Physiol. B, 133, 251-256.
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.1.37 agriculture first step to establish this enzyme as a possible biomarker for environmental contamination Rattus norvegicus
4.1.1.37 agriculture first step to establish this enzyme as a possible biomarker for environmental contamination Neohelice granulata

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.37 0.0015
-
 8-carboxylporphyrinogen pH 6.8, 37°C Rattus norvegicus
4.1.1.37 0.0105
-
 8-carboxylporphyrinogen pH 6.8, 37°C Neohelice granulata

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.37 48000
-
 gel filtration Neohelice granulata

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.37 Uroporphyrinogen III Rattus norvegicus fifth enzyme of the haem biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III Neohelice granulata fifth enzyme of the heme biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III Rattus norvegicus Wistar fifth enzyme of the haem biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.37 Neohelice granulata
-
 intertidal grapsid crab
-
4.1.1.37 Rattus norvegicus
-
 Wistar strain
-
4.1.1.37 Rattus norvegicus
-
 rat, Wistar
-
4.1.1.37 Rattus norvegicus Wistar
-
 Wistar strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.37
-
 Rattus norvegicus
4.1.1.37
-
 Neohelice granulata

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.37 8-carboxylporphyrinogen
-
 Rattus norvegicus coproporphyrinogen(4-COOH) + CO2
-
 ?
4.1.1.37 8-carboxylporphyrinogen
-
 Neohelice granulata coproporphyrinogen(4-COOH) + CO2
-
 ?
4.1.1.37 8-carboxylporphyrinogen
-
 Rattus norvegicus Wistar coproporphyrinogen(4-COOH) + CO2
-
 ?
4.1.1.37 Uroporphyrinogen III
-
 Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III
-
 Neohelice granulata Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III fifth enzyme of the haem biosynthetic pathway Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III fifth enzyme of the heme biosynthetic pathway Neohelice granulata Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III
-
 Rattus norvegicus Wistar Coproporphyrinogen III + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III fifth enzyme of the haem biosynthetic pathway Rattus norvegicus Wistar Coproporphyrinogen III + 4 CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.37 ch-UroD
-
 Neohelice granulata
4.1.1.37 rl-UroD
-
 Rattus norvegicus
4.1.1.37 UroD
-
 Rattus norvegicus
4.1.1.37 UroD
-
 Neohelice granulata
4.1.1.37 uroporphyrinogen decarboxylase
-
 Rattus norvegicus
4.1.1.37 uroporphyrinogen decarboxylase
-
 Neohelice granulata

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.37 47
-
-
 Rattus norvegicus
4.1.1.37 47
-
-
 Neohelice granulata

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.37
-
 70 activity increases with temperature up to 47°C, decreases at 53°C Rattus norvegicus
4.1.1.37
-
 70 activity increases with temperature up to 47°C, decreases at 53°C Neohelice granulata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.37 6.8
-
-
 Rattus norvegicus
4.1.1.37 7.2
-
-
 Neohelice granulata

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.37 6.1 7.9
-
 Rattus norvegicus
4.1.1.37 6.4 7.9
-
 Neohelice granulata