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Literature summary extracted from

  • Dinh, T.P.; Freund, T.F.; Piomelli, D.
    A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation (2002), Chem. Phys. Lipids, 121, 149-158.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.23 expressed in COS-7 and HeLa cells Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.23 arachidonoyl trifluoromethylketone 50% inhibition at 0.0025 mM Rattus norvegicus
3.1.1.23 hexadecylsufonyl fluoride 50% inhibition at 0.0062 mM Rattus norvegicus
3.1.1.23 methyl arachidonyl fluorophosphonate 50% inhibition at 0.0008 mM Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.23 cytosol after expression in HeLa cells Rattus norvegicus 5829
-
3.1.1.23 plasma membrane after expression in HeLa cells Rattus norvegicus 5886
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.23 33370
-
 calculated from amino acid sequence Rattus norvegicus
3.1.1.23 35000
-
 two isoforms of 35000 Da and 37000 Da, SDS-PAGE Rattus norvegicus
3.1.1.23 37000
-
 two isoforms of 35000 Da and 37000 Da, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.23 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.23 brain
-
 Rattus norvegicus
-
3.1.1.23 cerebellum
-
 Rattus norvegicus
-
3.1.1.23 cerebral cortex
-
 Rattus norvegicus
-
3.1.1.23 hippocampus
-
 Rattus norvegicus
-
3.1.1.23 thalamus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.23 2-arachidonoylglycerol + H2O
-
 Rattus norvegicus arachidonic acid + glycerol
-
 ?
3.1.1.23 2-monooleoylglycerol + H2O
-
 Rattus norvegicus oleic acid + glycerol
-
 r