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Literature summary extracted from

  • Zatta, P.; Ibn-Lkhayat-Idrissi, M.; Zambenedetti, P.; Kilyen, M.; Kiss, T.
    In vivo and in vitro effects of aluminum on the activity of mouse brain acetylcholinesterase (2002), Brain Res. Bull., 59, 41-45.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.7 aluminium lactate activates the enzyme in vitro and in vivo after oral treatment Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.7 0.46
-
 acetylthiocholine pH 7.5, 37°C, addition of aluminium lactate during measurement of activity Mus musculus
3.1.1.7 0.61
-
 acetylthiocholine pH 7.5, 37°C, addition of AlCl3 during measurement of activity Mus musculus
3.1.1.7 1
-
 acetylthiocholine pH 7.5, 37°C, after treatment with aluminium lactate for 3 months Mus musculus
3.1.1.7 1.16
-
 acetylthiocholine pH 7.5, 37°C, after treatment with AlCl3 for 3 months Mus musculus
3.1.1.7 2.5
-
 acetylthiocholine pH 7.5, 37°C addition of sodium lactate during measurement of activity Mus musculus
3.1.1.7 2.5
-
 acetylthiocholine pH 7.5, 37°C, addition of NaCl during measurement of activity Mus musculus
3.1.1.7 2.5
-
 acetylthiocholine pH 7.5, 37°C, after treatment with NaCl for 3 months Mus musculus
3.1.1.7 2.5
-
 acetylthiocholine pH 7.5, 37°C, after treatment with sodium lactate for 3 months Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.7 aluminium chloride activates the enzyme in vitro and in vivo after oral treatment Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.7 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.7 brain
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.7 acetylthiocholine + H2O
-
 Mus musculus acetate + thiocholine
-
 ?