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Literature summary extracted from

  • Wickramaratna, J.C.; Fry, B.G.; Aguilar, M.I.; Kini, R.M.; Hodgson, W.C.
    Isolation and pharmacological characterization of a phospholipase A2 myotoxin from the venom of the Irian Jayan death adder (Acanthophis rugosus) (2003), Br. J. Pharmacol., 138, 333-342.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.4 4-bromophenacyl bromide 1.8 mM, prevents myotoxicity caused by the enzyme Acanthophis rugosus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.4 13810
-
 mass spectrometry Acanthophis rugosus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.4 additional information Acanthophis rugosus enzyme causes myotoxicity but no significant neurotoxicity ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.4 Acanthophis rugosus
-
 death adder
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.4 venom
-
 Acanthophis rugosus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.4 1,2-dithio-deheptanoyl phosphatidylcholine + H2O
-
 Acanthophis rugosus ?
-
 ?
3.1.1.4 additional information enzyme causes myotoxicity but no significant neurotoxicity Acanthophis rugosus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.4 Acanmyotoxin-1
-
 Acanthophis rugosus