Literature summary extracted from

Sakamoto, H.; Mashima, T.; Kizaki, A.; Dan, S.; Hashimoto, Y.; Naito, M.; Tsuruo, T.
Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis (2000), Blood, 95, 3214-3218.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4.4.1.5	glutathione-methylglyoxal hemithioacetal	Homo sapiens	glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione	(R)-S-lactoylglutathione	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.4.1.5	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.4.1.5	glutathione-methylglyoxal hemithioacetal	glutathione-methylglyoxal hemithioacetal is formed non-enzymatically from methylglyoxal and glutathione	Homo sapiens	(R)-S-lactoylglutathione	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.4.1.5	Glo1	-	Homo sapiens
4.4.1.5	glyoxalase I	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)